Skin cancer treatment and reconstruction

Basal cell carcinoma, red nodule on the skin

Skin Cancer: Symptoms, Types, Diagnosis, and Treatment

Skin cancer is the most common type of cancer worldwide. It develops when skin cells grow abnormally, usually due to damage from ultraviolet (UV) radiation from the sun or tanning beds. When detected early, most forms of skin cancer can be treated effectively, often with simple surgical procedures. However, if left untreated, some types can spread and become life-threatening.

Causes and Risk Factors

Skin cancer is most often caused the following risk factors:

  • Fair skin, light eyes, and hair color.

  • Frequent sunburns, especially in childhood.

  • Use of tanning beds.

  • Family history of skin cancer.

  • Weakened immune system (HIV, organ transplant, long-term medications).

  • Older age (but melanoma is also common in younger adults).

  • Chronic scars or burns.

Signs and Symptoms

See a dermatologist/plastic surgeon if you notice:

  • A new growth or sore that does not heal within 3 weeks.

  • Changes in an existing mole (color, size, shape).

  • Itching, bleeding, or tenderness in a mole or spot.

  • Rough, scaly patches or ulcers that don’t go away.

Skin cancer treatment algorithm

Diagnosis: How Skin Cancer Is Detected

Diagnosis is usually made with a skin biopsy:

  • Excisional biopsy – the entire lesion is removed (preferred for pigmented lesions). For a lesion suspicious for melanoma, complete excisional biopsy with narrow margins is generally preferred when technically feasible.

  • Incisional biopsy – a part of the lesion is removed (for large or complex cases or areas of cosmetic concern like eyes, ears and nose).

    The pathologist then examines the tissue under a microscope to confirm if it is cancer, identify the type of tumor, and assess its risk features. These findings guide the next steps, whether the lesion should be excised with wider margins or whether no further treatment is needed.

Skin cancer treatment

  • Surgical excision: Most localized skin cancers are treated surgically. The required margin depends on the tumor type, size, location and pathological risk factors. In selected high-risk tumors or anatomically sensitive areas, Mohs micrographic surgery can provide complete margin assessment while preserving as much healthy tissue as possible.

  • Cryotherapy: Freezing the lesion with liquid nitrogen, mainly for early or precancerous spots.

  • Radiation therapy: Used when surgery is not possible or after surgery when certain types of skin cancer exhibit high risk factors.

  • Chemotherapy / Immunotherapy: For advanced or metastatic melanoma/SCC.

Reconstruction After Skin Cancer Surgery

Removing the cancer safely comes first. Reconstruction is then planned according to the size, depth and location of the resulting defect, with the aim of restoring normal anatomy and function while keeping scars as discreet as reasonably possible.

  • Primary closure: Smaller defects can often be closed directly, positioning the scar along natural skin lines when possible.

  • Local flaps: Nearby skin and soft tissue can be advanced, rotated or transposed into the defect. Because the tissue comes from the same anatomical region, it often provides the closest match in color, thickness and texture.

  • Skin grafts: Skin can be transferred from another area when local tissue is insufficient or when a graft is better suited to the defect.

  • Complex reconstruction: Defects involving the nose, eyelids, lips or ears may require combinations of flaps, grafts or staged procedures to restore both form and function.

The simplest reconstruction is not always the best one, and the most complex reconstruction is not necessarily better. The technique is chosen according to the defect while keeping oncologic safety as the priority.

The reconstructive plan is determined by the tumor, the method of margin assessment and the resulting defect. Oncologic clearance always takes priority over reconstruction.

Reconstruction After Skin Cancer Surgery

Once a skin cancer has been completely removed, the next step is often reconstruction. The goal of reconstruction is not only to close the wound but also to restore both function and natural appearance.

  • Primary closure (stitches): For small lesions, the wound can usually be closed directly with sutures, leaving a fine scar.

  • Skin flaps: For larger or more complex wounds, surrounding tissue can be carefully rotated, advanced, or repositioned to cover the defect. Flaps use the patient’s own skin, which blends best in terms of texture and color.

  • Skin grafts: In some cases, skin is taken from another area of the body and transplanted to cover the surgical site. This is common when there isn’t enough local tissue to close the wound.

  • Specialized techniques: For sensitive areas such as the nose, lips, eyelids, or ears, advanced reconstructive methods (combining all of the above) are used to maintain normal function while minimizing visible scarring.

Reconstruction is always planned with a balance between oncologic safety (making sure all cancer is removed with clear margins) and aesthetic outcome.

Close-up of a nose with a bilobed flap marked on it before excision of a lesion on the tip of the nose
Close-up of a nose with a bilobed flap after reconstruction on the tip of the nose

A basal cell carcinoma on the nose reconstructed with a bilobed flap. This will fade in time.

Frequently asked questions in my practice